| | Dear Friend of Scientific American,
I'm excited to share our February issue with you, particularly the cover story on fantastical blobs. In this feature, science writer Philip Ball describes the cutting-edge research on teensy blobs called biomolecular condensates that are taking over cellular biology. These specks of protein and RNA play crucial roles in cells, from holding together damaged DNA strands, to keeping cells at optimal temperatures, to helping to regulate genes. When the condensates malfunction, however, the result can lead to neurodegenerative diseases. One such disease, Alzheimer's is having a big moment. Genetics counselor Laura Hercher walks us through new blood tests that reveal telltale biomarkers of Alzheimer's long before the onset of cognitive symptoms. With these tests, doctors could diagnose someone with "pre-Alzheimer's." Hercher reveals the good and bad of such an advance. Exciting research reveals a simple way to boost teenagers' brain development: Encourage them to ponder deep questions and what's beyond the here and now. This transcendent thinking helps develop coordination between brain circuits and improve life satisfaction.
Best wishes, Jeanna Bryner Acting Editor in Chief | | | Tiny specks called biomolecular condensates are leading to a new understanding of the cell. | According to expert recommendations, the diagnosis of Alzheimer's can proceed by detecting the disease's underlying biology—even before the onset of cognitive decline. | A style of teaching that gets adolescents to reflect beyond the here and now may help their brain grow in ways that enhance life. | The best view yet of the Cassiopeia A supernova remnant reveals new secrets. | DNA inherited from Neandertals may influence modern human cognition. | Spreading crushed stone across farm fields could inexpensively pull CO2 from the air while also increasing yields. But it would require a mountain of mining. | To view this email as a web page, go here.
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